[HTML][HTML] Foot-and-mouth disease virus: immunobiology, advances in vaccines and vaccination strategies addressing vaccine failures—an Indian perspective

RK Singh, GK Sharma, S Mahajan, K Dhama… - Vaccines, 2019 - mdpi.com
… whole virus inactivated vaccine is used in the FMDCP in India… Due to the high rate of virus
mutation, strain differences can … sufficiently stable to transport in the tropical conditions of India. …

A single amino acid substitution in the VP2 protein of Indian foot‐and‐mouth disease virus serotype O vaccine strain confers thermostability and protective immunity in …

JK Biswal, BP Sreenivasa… - … Emerging Diseases, 2022 - Wiley Online Library
… Prophylactic vaccination using inactivated FMD virus (FMDV) antigen is … inactivation kinetics
and genetic stability of the mutant … The mean difference between the vaccine types was not …

[HTML][HTML] … Antigen Yield and Virus Inactivation Conditions for the Production of the Candidate Foot-and-Mouth Disease Recombinant Vaccine Strain Asia1 Shamir-R in …

JY Kim, SY Park, G Lee, SH Park, JS Jin, D Kim… - Viruses, 2024 - mdpi.com
… Although there was no difference in the virus titer as the virus culture size increased, the …
in a biosafety level 3 facility; therefore, another validation method for virus inactivation, called …

[HTML][HTML] Efficacy of binary ethylenimine in the inactivation of foot-and-mouth disease virus for vaccine production in South Korea

JY Kim, SY Park, JS Jin, D Kim, JH Park, SH Park… - Pathogens, 2023 - mdpi.com
… a method for the efficient production of the inactivating agent, … Based on this, we compared
the inactivation of four FMDVs … to the high stability of our four vaccine candidate strains in this …

[HTML][HTML] … of Foot-and-Mouth Disease (FMD) Virus Asia1 Genotype-V as an FMD Vaccine Candidate: Study on Vaccine Antigen Production Yield and Inactivation …

JY Kim, SY Park, SH Park, G Lee, JS Jin, D Kim… - Vaccines, 2024 - mdpi.com
… was developed using a genetic recombination method (Asia1/MOG/05-… There was a difference
in antigen yield even at similar titers; … more stable than other foreign FMD vaccine strains. …

[HTML][HTML] Formulation enhanced the stability of Foot-and-mouth virus and prolonged vaccine storage

J Li, Y Chang, S Yang, G Zhou, Y Wei - Virology Journal, 2022 - Springer
Foot-and-mouth disease (FMD) is a highly contagious viralInactivated whole virus vaccine
is superior to other vaccines due … inactivation of formulated virus increased to 64 C, compared

[HTML][HTML] Thermostable negative-marker foot-and-mouth disease virus serotype O induces protective immunity in guinea pigs

HB Ranjitha, VV Dhanesh, M Hosamani… - Applied Microbiology …, 2023 - Springer
… DIVA compliant stable vaccine, … vaccinated with inactivated thermostable virus with Y2098F
produced higher neutralizing antibody titer compared to the parental O IND/R2/1975 vaccine

Comparison of chemical extraction methods for determination of 146S content in foot‐and‐mouth disease oil‐adjuvanted vaccine

P Saravanan, Z Iqbal, DPR Selvaraj… - Journal of applied …, 2020 - academic.oup.com
… by mass vaccination with inactivated oil‐adjuvanted vaccine. … of India across the states which
advocate biannual vaccinationStability of the virus capsid decides the thermostability and …

Immunogenicity and protective efficacy of 3A truncated negative marker foot-and-mouth disease virus serotype A vaccine

VV Dhanesh, M Hosamani… - Applied microbiology …, 2020 - Springer
Immunization of guinea pigs with the inactivated vaccine … to check the genomic stability of
the virus in the deleted region. … developed in this study in comparison with PrioCHECK® FMDV …

[HTML][HTML] Foot-and-mouth disease vaccines: recent updates and future perspectives

M Kamel, A El-Sayed, H Castañeda Vazquez - Archives of virology, 2019 - Springer
… through vaccination with inactivated vaccines. These … vaccines are considered to be more
stable than previous … A trial was conducted recently to compare the immune response to this …